Journal: Sensors (Basel, Switzerland)

Article Title: Pose2Sim: An End-to-End Workflow for 3D Markerless Sports Kinematics—Part 2: Accuracy

doi: 10.3390/s22072712

Figure Lengend Snippet: Triangulated anatomical markers and clusters (dark green), calculated joint centers (light green), and OpenPose BODY_25B keypoints (pink) on a textured mesh. OpenPose’s eyes and ears keypoints were excluded . Mesh opacity was set to 0.5 in order to make all points visible. This view made it possible to precisely place OpenPose triangulated keypoints on the OpenSim model.

Article Snippet: Pose2Sim comes with a generic OpenSim skeletal model that has been slightly improved since the last study [ ].

Techniques:

Journal: Sensors (Basel, Switzerland)

Article Title: Pose2Sim: An End-to-End Workflow for 3D Markerless Sports Kinematics—Part 2: Accuracy

doi: 10.3390/s22072712

Figure Lengend Snippet: Pose2Sim full pipeline: (1) OpenPose 2D joint detection; (2i) camera calibration; (2ii–iv) tracking the person of interest, triangulating his coordinates, and filtering them; (3) constraining the 3D coordinates to a physically consistent OpenSim skeletal model.

Article Snippet: Pose2Sim comes with a generic OpenSim skeletal model that has been slightly improved since the last study [ ].

Techniques:

Journal: Diabetologia

Article Title: Elevated ITGA1 levels in type 2 diabetes: implications for cardiac function impairment

doi: 10.1007/s00125-024-06109-4

Figure Lengend Snippet: Plasma proteomic analysis comparing participants with type 2 diabetes with or without HFpEF. ( a ) Principal component analysis demonstrates distinguishable separation between the two groups. ( b ) Volcano plot showing differential proteins between the two groups. A total of 235 proteins exhibited significant alterations, including 81 downregulated and 154 upregulated proteins in the HFpEF group compared with the non-HFpEF group. ( c ) KEGG enrichment analysis revealed that the differentially expressed proteins were primarily involved in ten specific pathways. Among these pathways, ‘hypertrophic cardiomyopathy’ was closely linked to HFpEF. ( d ) Correlation analysis examining the relationship between proteins enriched in the ‘hypertrophic cardiomyopathy’ pathway and echocardiography indicators. ITGA1 demonstrated a stronger correlation with echocardiography indicators related to cardiac structure (left atrial diameter to left ventricular end systolic volume) and function (ejection fraction to e′ septal) compared with the other seven biomarkers. ACTB, actin β; CACNA2D1, calcium voltage-gated channel auxiliary subunit α2δ1; DES, desmin; Dim1, dimension 1; Dim2, dimension 2; e' lat, e' lateral; e' sep, e' septal; LAD, left atrial diameter; LVESV, left ventricular end systolic volume; MYH7, myosin heavy chain 7; PCA, principal component analysis; PPAR, peroxisome proliferator-activated receptor

Article Snippet: Standard two-dimensional echocardiography and tissue Doppler imaging was performed on recruited participants with a commercially available echocardiography system (VingmedE9; General Electric Vingmed Ultrasound, Horten, Norway) by skilled operators who were blinded to the participants’ clinical and biochemical characteristics.

Techniques: Clinical Proteomics